![]() Rehabilitation including RSS enhanced sensorimotor recovery more effectively than standard therapy alone. Repetitive sensory stimulation was well tolerated and accepted, and no adverse events were observed. After 2 weeks of the intervention, patients in the group receiving standard therapy with RSS showed significantly better restored sensorimotor function than the control group (standardized mean difference 0.57 95% CI -0.013-1.16 p = 0.027) RSS treatment was superior in all domains tested. Before treatment, sensorimotor performance between groups was balanced (p = 0.237). Data of 25 patients were not completed because they were transferred to another hospital, resulting in n = 23 for each group. Seventy one eligible patients were enrolled and randomly assigned to receive RSS treatment (n = 35) or sham RSS (n = 36). In addition, tolerability and side effects of RSS intervention were recorded. Data from these quantitative tests were combined into a total performance index serving as primary outcome measure. Before and after the intervention, we assessed light-touch and tactile discrimination, proprioception, dexterity, grip force, and subtasks of the Jebsen Taylor hand-function test for the non-affected and the affected hand. RSS consisted of intermittent 20 Hz electrical stimulation applied on the affected hand for 45 min/day, 5 days per week, for 2 weeks, and was transmitted using custom-made stimulation-gloves with built-in electrodes contacting each fingertip separately. Patients were masked to treatment allocation. Patients with subacute unilateral ischemic stroke were randomly assigned to receive standard therapy in combination with RSS or with sham RSS. Here, we investigated whether RSS reduces sensorimotor upper limb impairment in patients with subacute stroke more effectively than conventional therapy.Ī single-blinded sham-controlled clinical trial assessed the effectiveness of RSS in treating sensorimotor deficits of the upper limbs. In healthy subjects, RSS leads to widespread sensorimotor cortical reorganization paralleled by improved sensorimotor behavior. An incomplete uninstallation of a program may cause problems, which is why thorough removal of programs is recommended.Repetitive sensory stimulation (RSS) adapts the timing of stimulation protocols used in cellular studies to induce synaptic plasticity. There could be other causes why users may not be able to uninstall Syncovery.
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